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An NIH-NIBIB Biomedical Technology Resource





The Developmental Resource for Biophysical Imaging Opto-Electronics (DRBIO) is a research resource located jointly in the Department of Biomedical Engineering and the School of Applied and Engineering Physics at Cornell University.

DRBIO focuses on the creation and optimization of quantitative optical instrumentation for biophysical and biomedical research, specifically multiphoton laser-scanning microscopy for biological research and biomedical imaging.

The primary instrumentation development core and collaborative imaging facility of DRBIO now resides in basement low vibration facility in the newly opened Weill Hall

The fiber laser development core (Xu lab) and our collaborative multiphoton endoscopy center directed by Professor Watt Webb is housed in the Clark Hall of Science where DRBIO was founded by Dr. Webb in 1988.


Our mission here at DRBIO is to conceive, develop and demonstrate tools for an increased understanding of fundamental biochemical and biophysical events in cells, tissues and living animals. We focus primarily on optical instrumentation since light is especially well-suited for these demands. The emergence of new fluorescent and photochemical probes coupled with new developments in mode-locked lasers, sensitive low-noise detectors and fast data acquisition capabilities have given us the needed pieces to build instrumentation with unparalleled specificity, sensitivity and versatility. We seek to remain at the forefront of these new developments, driven by our internal research, the needs of our biomedical collaborators, and close collaborations with our industrial and technological partners. Because of our experience with biological microscopy and spectroscopy, we operate as a biomedical engineering interface between the biological community and the technical community.







: Lab Schedule

: Group Presentations

: Protocols

- Biomedical Engineering
- Applied & Eng. Physics
- College of Engineering
- Cornell University

- Bio-Imaging Seminar
- Biophysics Seminar

- MPM Documentation
- DRBIO Subversion


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