Intellectual
Property/Patents
Watt
W. Webb
I38/D-4080/Active.
Xu, C. and W.W. Webb, “A Coaxial Optical Instrumentation Design for
Incorporation of Multiphoton Microscopy into Medical Endoscopy,” invention
disclosure filed 3/2007, US Provisional patent application #60/987,868
filed 11/14/2007.
I37/D-4114/Active. Xu, C. and W.W. Webb, “Non-Invasive Assays of
Fluorescent Indicators of Disease States in Tissue by Multiphoton Excitation
(MPE),” invention
disclosure filed 3/2007, US Provisional patent application #60/987,270
filed 11/12/2007.
I36/D-2216/Active. Webb, W.W., “Use of Multiphoton Excitation Through
Optical Fibers for Fluorescence Spectroscopy in Conjunction with Optical
Biopsy Needles and Endoscopes,” Foreign Patents: Issued as “Multiphoton
Excitation Through Optical Fibers for Fluorescence Spectroscopy,” Australian
patent #779659 (06/02/2005) and New Zealand patent #520257 (02/09/2006);
US Patent #6,580,941 (06/17/2003 – Utility Patent), US Patent #6,839,586
(01/04/2005 – Continuation Patent).
I35/D-2694/Active. Bradley T. Hyman, Richard Christie, Brian Bacskai,
Watt W. Webb, and Warren R. Zipfel, “In-Vivo Alzheimer's Diagnostic Using
Multiphoton Microscopy,” (Joint Owner is Mass. Gen. Hospital Ref.
No. 1705). Many Foreign patents issued (Great Britain, France, Austria,
Sweden, Netherlands, Italy, Germany, Switzerland, Patent #1347731, 04/25/2007);
US Patent status under prosecution.
I34/D-2385/Active.
Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G. Craighead, and M.
Foquet, “Nucleotides,” US Patent Application
number 20070026447, filed 2/1/2007.
I33/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Labeled nucleotide phosphate (NP)
probes,” US
Patent Application number 20060211010, filed 9/21/2006.
I32/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “High speed nucleic acid sequencing,” US
Patent Application number 20060188900, filed 8/24/2006
I31/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Terminal-phosphate-labeled nucleotides,” US
Patent application number 20060160113, filed 7/20/2006
I30/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Methods for analyzing nucleic acid
sequences,” US
Patent application number 20060154288, filed 7/13/2006
I29/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Methods for detecting nucleic acid
analyte,” US
Patent application number 20060134666, filed 6/22/2006
I28/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Sequencing nucleic acid using tagged
polymerase and/or tagged nucleotide,” US Patent application number
20060078937, filed 4/13/2006
I27/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Reagents containing terminal-phosphate-labeled
nucleotides for nucleic acid sequencing,” US Patent application
number 20060057606, filed 3/16/2006
I26/D-3845/Active. Williams, R.M., W.R. Zipfel, and W.W. Webb, “High
resolution second harmonic generation (SHG) imaging and spectroscopy
for assaying lesions or damage in collagenous tissue,” invention
disclosure filed 2/2/2006
I25. Tewari, A. and W.W. Webb, “Endoscope capable of MPM and SGH
microscopy; Endoscope capable of MPM and SGH microscopy and compatible
with the daVinci robotic surgical system; Methods to use MPM endoscopy
in nerve-sparing radical prostatectomy; Methods to use MPM endoscopy
in nerve-sparing retro-peritoneal lymph- node dissection (RPLND),” Invention
disclosure filed 11/15/2005
I24/D3778/Active. Webb, W.W. and D.S. Scherr, “Multiphoton endoscope
and methods to diagnose and stage urologic malignancy, and monitor
response of urologic malignancies to treatment,” Invention disclosure
filed 10/18, 2005
I23/D-3711/Inactive. Pollack, L., H.Y. Park, L.W. Kwon, and W.W. Webb, “Microfluidic
Mixer for Microsecond Kinetic Studies,” US Letters Patent Application,
Serial No. 60/691,879, filed 6/17/2005.
I22/D-3378/Active. Wiesner, U., H. Ow, D.R. Larson, and W.W. Webb, “Fluorescent
Silica-Based Nanoparticles,” International Provisional Patent
Application No. PCT/US2003/037963 filed 11/26/2003, US Patent Application
20060183246
filed 8/17/2006, Licensed to Hybrid Silica Technologies, Inc.
I21/D-3405/Inactive. Dombeck, D.A., W.W. Webb, M. Blanchard-Desce, O.
Mongin, and T. Mallegol, “Nonlinear Optical Detection of Fast
Cellular Electrical Activity,” US Provisional patent application
No. 60/539,380 filed 1/27/2004, US Patent Application No. 11/044,889
filed 1/27/2005
I20/D-3153/Active. Gaeta, A., D. Ouzounov, W.R. Zipfel, and W.W. Webb, “Fiber
delivery and collection system for biological applications such as
multiphoton microscopy,” US Full patent application filed, 20050043636
(2005); EP1664854 A2 (2006)
I19/D-2908/Active. Levene, M.A., J. Korlach, S.W. Turner, H.G. Craighead,
and W.W. Webb, “Zero-mode clad waveguides for performing spectroscopy
with confined effective observation volumes,” US Patent 6,917,726
(2005), US Continuation Patent 7,013,054 (2006), US Patent 7,181,122
(2007)
I18/D-2721/Inactive. Michael Levene, Daniel T. Larson, and Watt W.
Webb, “Optical
Field Enhancement,” U.S. Utility Patent Application US2003/0092005
(2003)
I17/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Method for sequencing nucleic acid
molecules,” US
Patent 7,056,676 (2006)
I16/D-2385/Active. Jonas Korlach, Watt W. Webb, Michael Levene, Stephen
Turner, Harold G. Craighead, and Mathieu Foquet, “Method for
sequencing nucleic acid molecules,” US Patent 7,052,847 (2006)
I15/D-2385/Active. Jonas Korlach, Watt W. Webb, Michael Levene, Stephen
Turner, Harold G. Craighead, and Mathieu Foquet, “Method for
sequencing nucleic acid molecules,” US Patent 7,033,764 (2006)
I14/D-2385/Active. Korlach, J., W.W. Webb, M. Levene, S. Turner, H.G.
Craighead, and M. Foquet, “Single Molecule DNA Sequencing” European
Patent Application EP1179085 A1 (2002), U.S. Patent 7,056,661 (2006)
I13/D-1828/Active. Chunhui (Chris) Xu and Watt W. Webb, “Multi-Photon
Laser Microscopy” U.S. Patent 6,344,653 (2002) EP852716 B1 (2005).
Licensed to Carl Zeiss Jena GmbH.
I12/D-1828/Active. Chunhui (Chris) Xu and Watt W. Webb, “Multi-Photon
Laser Microscopy” U.S. Patent 6,166,385 (2000) EP500717 B2 (2003).
Licensed to Carl Zeiss Jena GmbH.
I11/D1296/Inactive. Lucien Ghislain and Watt W. Webb, “Scanning
Force Microscopy Using an Optical Trap” U.S. Patent 5,445,011 (1995).
License to Digital Instruments now terminated.
I10/D-1120/Inactive. J. H. Strickler and W. W. Webb, “Method for
Three Dimensional Optical Data Storage and Retrieval” U.S. Patent:
5,289,407 (1994). European Patent 595999 (1999).
I9/D-932/Active. W. Denk, W. W. Webb and J. H. Strickler, “Two
Photon Laser Scanning Microscopy” U. S. Patent 5,034,613 (1991).
Japanese Patent 2,848,952 (1998). European Patent 0500717B1 (1998). Licensed
to Carl Zeiss Jena GmbH.
I8/D-0715/Inactive. Neil Gershenfeld, Watt W. Webb, Jeffrey E. VanCleve,
Joseph V. Mantese and Eric T. Swartz, “Percolating Cermet Thin
Film Thermistor” U. S. Patent 4,906,968 (1990)
I7/D0583/Inactive. W. W. Webb and R. D. Ferguson, “Multidimensional
Vorticity Measurement Optical Probe System” U. S. Patent 4,664,513
(1987).
I6/D0373/Inactive. L. S. Barak, E. A. Nothnagel, W. W. Webb and R. R.
Yocum, “Acidic
Phallotoxin Derivatives and Methods of Preparation” U. S. Patent
4,489,001 (1984). License to Molecular Probes has expired.
I5/D386/Inactive. W. W. Webb and M. B. Frish, “Direct Measurement
of Vorticity by Optical Probe” U. S. Patent 4,385,830 (1983).
I4/D0373/Inactive. L. S. Barak, E. A. Nothnagel, W. W. Webb and R. R.
Yocum, “NBD-Acidic
Phallotoxins and their use in the Fluorescence Staining of F-Actin” U.
S. Patent 4,387,088 (1983). License to Molecular Probes has expired.
I3. W. W. Webb and W. J. Allen, “Process for Production of Long
Metallic Whiskers” U. S. Patent 3,144,358 (1964) (plus many foreign
patents on same invention).
I2. W. W. Webb, W. A. Whissler and W. D. Forgeng, “Process for Preparing
Virtually Perfect Alumina Crystals” U. S. Patent 3,011,870 (1961).
I1. W. W. Webb, “Metal Arc Welding” U. S. Patent 2,868,948
(1959) (Plus many foreign patents on same invention).
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