Granule pH cycling

Single granule exocytosis and recycling in RBL mucosal mast cells

Granule recycling at the single granule level can be measured with LysoSensor, a granule pH sensor. Upon stimulation, granules release. After release, 60% of the granules reacidify and re-release on a 2-3 min. timescale. Each granule experiences on average 3 release events.

Home \| Contacts \| FAQ’s \| Maps \| Cornell Biophysics \| Jobs \| Funding \| Links \| Search DRBIO



Single granule exocytosis and recycling in RBL mucosal mast cells Granule recycling at the single granule level can be measured with LysoSensor, a granule pH sensor. Upon stimulation, granules release. After release, 60% of the granules reacidify and re-release on a 2-3 min. timescale. Each granule experiences on average 3 release events.